D481-1673 Screening compound: N-(1H-1,3-benzodiazol-2-yl)-2-(2-{4-[(3-fluorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide

D481-1673 Screening compound: N-(1H-1,3-benzodiazol-2-yl)-2-(2-{4-[(3-fluorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide
D481-1673 Screening compound: N-(1H-1,3-benzodiazol-2-yl)-2-(2-{4-[(3-fluorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D481-1673
N-(1H-1,3-benzodiazol-2-yl)-2-(2-{4-[(3-fluorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D481-1673

Molecular Formula

C24H21FN6OS (C24 H21 FN6 OS)

Compound Name

N-(1H-1,3-benzodiazol-2-yl)-2-(2-{4-[(3-fluorophenyl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)acetamide

IUPAC name

N-(1H-13-benzodiazol-2-yl)-2-(2-{4-[(3-fluorophenyl)methyl]-35-dimethyl-1H-pyrazol-1-yl}-13-thiazol-4-yl)acetamide

SMILES

Cc1c(Cc2cc(F)ccc2)c(C)nn1-c1nc(CC(Nc2nc(cccc3)c3[nH]2)=O)cs1

InChI

InChI=1S/C24H21FN6OS/c1-14-19(11-16-6-5-7-17(25)10-16)15(2)31(30-14)24-26-18(13-33-24)12-22(32)29-23-27-20-8-3-4-9-21(20)28-23/h3-10,13H,11-12H2,1-2H3,(H2,27,28,29,32)

InChI Key

FRMDTLVBRWJLKB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27588931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.461

Distribution Coefficient, logD

4.460

Water Solubility, LogSw

-4.48

Polar Surface Area

68.004

Acid Dissociation Constant (pKa)

11.33

Base Dissociation Constant (pKb)

4.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D481-1673 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Proteases
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with D481-1673 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D481-1673?
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What is the minimum amount of D481-1673 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D481-1673
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D481-1673
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D481-1673 available by request