D517-1064 Screening compound: 5-(1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-6-(naphthalen-2-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione

D517-1064 Screening compound: 5-(1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-6-(naphthalen-2-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione
D517-1064 Screening compound: 5-(1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-6-(naphthalen-2-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D517-1064
5-(1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-6-(naphthalen-2-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D517-1064

Molecular Formula

C25H18N4O3 (C25 H18 N4 O3)

Compound Name

5-(1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-6-(naphthalen-2-yl)-1H,2H,3H,4H,7H-pyrrolo[2,3-d]pyrimidine-2,4-dione

IUPAC name

5-(1-methyl-2-oxo-23-dihydro-1H-indol-3-yl)-6-(naphthalen-2-yl)-1H2H3H4H7H-pyrrolo[23-d]pyrimidine-24-dione

SMILES

CN(C(C1c2c(-c3cc4ccccc4cc3)[nH]c(NC(N3)=O)c2C3=O)=O)c2c1cccc2

InChI

InChI=1S/C25H18N4O3/c1-29-17-9-5-4-8-16(17)18(24(29)31)19-20-22(27-25(32)28-23(20)30)26-21(19)15-11-10-13-6-2-3-7-14(13)12-15/h2-12,18H,1H3,(H3,26,27,28,30,32)/t18-/m0/s1

InChI Key

VDAMSWRHOTVOFO-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27590622

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.487

Distribution Coefficient, logD

2.806

Water Solubility, LogSw

-4.05

Polar Surface Area

74.793

Acid Dissociation Constant (pKa)

6.82

Base Dissociation Constant (pKb)

-1.44

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.00

D517-1064 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with D517-1064 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D517-1064?
Check Price and Availability of D517-1064, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D517-1064 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D517-1064
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D517-1064
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D517-1064 available by request