D703-0050 Screening compound: (2E)-N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-3-phenylprop-2-enamide

D703-0050 Screening compound: (2E)-N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-3-phenylprop-2-enamide
D703-0050 Screening compound: (2E)-N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-3-phenylprop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D703-0050
(2E)-N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-3-phenylprop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D703-0050

Molecular Formula

C22H18N4O2S (C22 H18 N4 O2 S)

Compound Name

(2E)-N-[4-ethyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2-yl]-3-phenylprop-2-enamide

IUPAC name

(2E)-N-[4-ethyl-5-(3-phenyl-124-oxadiazol-5-yl)-13-thiazol-2-yl]-3-phenylprop-2-enamide

SMILES

CCc1c(-c2nc(-c3ccccc3)no2)sc(NC(/C=C/c2ccccc2)=O)n1

InChI

InChI=1S/C22H18N4O2S/c1-2-17-19(21-25-20(26-28-21)16-11-7-4-8-12-16)29-22(23-17)24-18(27)14-13-15-9-5-3-6-10-15/h3-14H,2H2,1H3,(H,23,24,27)

InChI Key

MRHNZLILCIMJFX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.064

Distribution Coefficient, logD

6.063

Water Solubility, LogSw

-5.57

Polar Surface Area

65.834

Acid Dissociation Constant (pKa)

10.02

Base Dissociation Constant (pKb)

-0.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

D703-0050 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with D703-0050 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D703-0050?
Check Price and Availability of D703-0050, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D703-0050 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D703-0050
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D703-0050
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D703-0050 available by request