D715-1334 Screening compound: 4-chloro-N-{4-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-1,3-thiazol-2-yl}benzene-1-sulfonamide

D715-1334 Screening compound: 4-chloro-N-{4-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-1,3-thiazol-2-yl}benzene-1-sulfonamide
D715-1334 Screening compound: 4-chloro-N-{4-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-1,3-thiazol-2-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D715-1334
4-chloro-N-{4-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-1,3-thiazol-2-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D715-1334

Molecular Formula

C20H18ClN3O3S2 (C20 H18 ClN3 O3 S2)

Compound Name

4-chloro-N-{4-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-1,3-thiazol-2-yl}benzene-1-sulfonamide

IUPAC name

4-chloro-N-{4-[2-oxo-2-(1234-tetrahydroisoquinolin-2-yl)ethyl]-13-thiazol-2-yl}benzene-1-sulfonamide

SMILES

O=C(Cc1csc(NS(c(cc2)ccc2Cl)(=O)=O)n1)N(CC1)Cc2c1cccc2

InChI

InChI=1S/C20H18ClN3O3S2/c21-16-5-7-18(8-6-16)29(26,27)23-20-22-17(13-28-20)11-19(25)24-10-9-14-3-1-2-4-15(14)12-24/h1-8,13H,9-12H2,(H,22,23)

InChI Key

NHBFGRDAMGJRBC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08954206

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.97

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.275

Distribution Coefficient, logD

2.224

Water Solubility, LogSw

-4.54

Polar Surface Area

67.212

Acid Dissociation Constant (pKa)

5.35

Base Dissociation Constant (pKb)

-2.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

D715-1334 in Drug Discovery

Included in Screening Libraries

New Agro Library (44492 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro
Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D715-1334 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D715-1334?
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What is the minimum amount of D715-1334 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D715-1334
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D715-1334
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D715-1334 available by request