D718-0245 Screening compound: 5-(BIPHENYL-4-YL)-1,3-DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE

D718-0245 Screening compound: 5-(BIPHENYL-4-YL)-1,3-DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE
D718-0245 Screening compound: 5-(BIPHENYL-4-YL)-1,3-DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-0245
5-(BIPHENYL-4-YL)-1,3-DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-0245

Molecular Formula

C21H17N3O2 (C21 H17 N3 O2)

Compound Name

5-(BIPHENYL-4-YL)-1,3-DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE

IUPAC name

5-{[11'-biphenyl]-4-yl}-13-dimethyl-1H2H3H4H-pyrido[23-d]pyrimidine-24-dione

SMILES

CN(c(nccc1-c(cc2)ccc2-c2ccccc2)c1C(N1C)=O)C1=O

InChI

InChI=1S/C21H17N3O2/c1-23-19-18(20(25)24(2)21(23)26)17(12-13-22-19)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-13H,1-2H3

InChI Key

MQBDDTVUARLHTL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08088452

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.386

Distribution Coefficient, logD

4.386

Water Solubility, LogSw

-4.63

Polar Surface Area

41.129

Acid Dissociation Constant (pKa)

28.31

Base Dissociation Constant (pKb)

2.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.52

D718-0245 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with D718-0245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-0245?
Check Price and Availability of D718-0245, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-0245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-0245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-0245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-0245 available by request