D718-0499 Screening compound: N~1~-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)-2-phenylacetamide

D718-0499 Screening compound: N~1~-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)-2-phenylacetamide
D718-0499 Screening compound: N~1~-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)-2-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D718-0499
N~1~-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)-2-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D718-0499

Molecular Formula

C24H21N3O (C24 H21 N3 O)

Compound Name

N~1~-(4-methyl-3-phenyl-3H-1,5-benzodiazepin-2-yl)-2-phenylacetamide

IUPAC name

n/a

SMILES

CC(C1c2ccccc2)=Nc(cccc2)c2N=C1NC(Cc1ccccc1)=O

InChI

InChI=1S/C24H21N3O/c1-17-23(19-12-6-3-7-13-19)24(26-21-15-9-8-14-20(21)25-17)27-22(28)16-18-10-4-2-5-11-18/h2-15,23H,16H2,1H3,(H,26,27,28)/t23-/m1/s1

InChI Key

LCHTZZBLBNMDQD-HSZRJFAPSA-N

MDL Number (MFCD)

MFCD08132008

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.895

Distribution Coefficient, logD

3.893

Water Solubility, LogSw

-4.11

Polar Surface Area

40.059

Acid Dissociation Constant (pKa)

10.66

Base Dissociation Constant (pKb)

4.98

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

D718-0499 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with D718-0499 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D718-0499?
Check Price and Availability of D718-0499, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D718-0499 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D718-0499
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D718-0499
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D718-0499 available by request