D725-0180 Screening compound: N-(4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)thiophene-2-carboxamide

D725-0180 Screening compound: N-(4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)thiophene-2-carboxamide
D725-0180 Screening compound: N-(4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D725-0180
N-(4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D725-0180

Molecular Formula

C17H11N3O2S (C17 H11 N3 O2 S)

Compound Name

N-(4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)thiophene-2-carboxamide

IUPAC name

N-(4-{[13]oxazolo[45-b]pyridin-2-yl}phenyl)thiophene-2-carboxamide

SMILES

O=C(c1cccs1)Nc(cc1)ccc1-c1nc(nccc2)c2o1

InChI

InChI=1S/C17H11N3O2S/c21-16(14-4-2-10-23-14)19-12-7-5-11(6-8-12)17-20-15-13(22-17)3-1-9-18-15/h1-10H,(H,19,21)

InChI Key

YPRMZQJHBPNXGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06636427

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.36

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.512

Distribution Coefficient, logD

3.512

Water Solubility, LogSw

-3.86

Polar Surface Area

51.532

Acid Dissociation Constant (pKa)

12.54

Base Dissociation Constant (pKb)

1.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

D725-0180 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Human Receptors Annotated Library (5376 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with D725-0180 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D725-0180?
Check Price and Availability of D725-0180, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D725-0180 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D725-0180
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D725-0180
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D725-0180 available by request