E002-1151 Screening compound: N-[(4-ethoxyphenyl)methyl]-5-(5-methyl-1H-indazol-1-yl)-5-oxopentanamide

E002-1151 Screening compound: N-[(4-ethoxyphenyl)methyl]-5-(5-methyl-1H-indazol-1-yl)-5-oxopentanamide
E002-1151 Screening compound: N-[(4-ethoxyphenyl)methyl]-5-(5-methyl-1H-indazol-1-yl)-5-oxopentanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E002-1151
N-[(4-ethoxyphenyl)methyl]-5-(5-methyl-1H-indazol-1-yl)-5-oxopentanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E002-1151

Molecular Formula

C22H25N3O3 (C22 H25 N3 O3)

Compound Name

N-[(4-ethoxyphenyl)methyl]-5-(5-methyl-1H-indazol-1-yl)-5-oxopentanamide

IUPAC name

n/a

SMILES

CCOc1ccc(CNC(CCCC(n2ncc3c2ccc(C)c3)=O)=O)cc1

InChI

InChI=1S/C22H25N3O3/c1-3-28-19-10-8-17(9-11-19)14-23-21(26)5-4-6-22(27)25-20-12-7-16(2)13-18(20)15-24-25/h7-13,15H,3-6,14H2,1-2H3,(H,23,26)

InChI Key

NGVUCNULXWJFCQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14835059

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.107

Distribution Coefficient, logD

3.107

Water Solubility, LogSw

-3.12

Polar Surface Area

58.070

Acid Dissociation Constant (pKa)

14.02

Base Dissociation Constant (pKb)

-2.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

E002-1151 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Nuclear receptors
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with E002-1151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E002-1151?
Check Price and Availability of E002-1151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E002-1151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E002-1151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E002-1151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E002-1151 available by request