E002-1621 Screening compound: ethyl 4-[(5-chloro-1H-indazole-1-carbonyl)amino]benzoate

E002-1621 Screening compound: ethyl 4-[(5-chloro-1H-indazole-1-carbonyl)amino]benzoate
E002-1621 Screening compound: ethyl 4-[(5-chloro-1H-indazole-1-carbonyl)amino]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E002-1621
ethyl 4-[(5-chloro-1H-indazole-1-carbonyl)amino]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E002-1621

Molecular Formula

C17H14ClN3O3 (C17 H14 ClN3 O3)

Compound Name

ethyl 4-[(5-chloro-1H-indazole-1-carbonyl)amino]benzoate

IUPAC name

ethyl 4-[(5-chloro-1H-indazole-1-carbonyl)amino]benzoate

SMILES

CCOC(c(cc1)ccc1NC(n1ncc2c1ccc(Cl)c2)=O)=O

InChI

InChI=1S/C17H14ClN3O3/c1-2-24-16(22)11-3-6-14(7-4-11)20-17(23)21-15-8-5-13(18)9-12(15)10-19-21/h3-10H,2H2,1H3,(H,20,23)

InChI Key

MPDGKEGYYSCUDL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00159920

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.77

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.417

Distribution Coefficient, logD

4.417

Water Solubility, LogSw

-4.40

Polar Surface Area

56.577

Acid Dissociation Constant (pKa)

12.20

Base Dissociation Constant (pKb)

-3.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

E002-1621 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Aging Library (44940 compounds)

Cardiovascular Library (22201 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cardiovascular
  • Cancer
  • Endocrine
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with E002-1621 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E002-1621?
Check Price and Availability of E002-1621, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E002-1621 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E002-1621
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E002-1621
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E002-1621 available by request