E014-0015 Screening compound: 1-[4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carbonyl]-4-phenylpiperazine

E014-0015 Screening compound: 1-[4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carbonyl]-4-phenylpiperazine
E014-0015 Screening compound: 1-[4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carbonyl]-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E014-0015
1-[4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carbonyl]-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E014-0015

Molecular Formula

C24H24N4OS (C24 H24 N4 OS)

Compound Name

1-[4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carbonyl]-4-phenylpiperazine

IUPAC name

1-[46-dimethyl-3-(1H-pyrrol-1-yl)thieno[23-b]pyridine-2-carbonyl]-4-phenylpiperazine

SMILES

Cc1c(c(-n2cccc2)c(C(N(CC2)CCN2c2ccccc2)=O)s2)c2nc(C)c1

InChI

InChI=1S/C24H24N4OS/c1-17-16-18(2)25-23-20(17)21(27-10-6-7-11-27)22(30-23)24(29)28-14-12-26(13-15-28)19-8-4-3-5-9-19/h3-11,16H,12-15H2,1-2H3

InChI Key

JDRDZVXWDKFMGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14837985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.55

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.860

Distribution Coefficient, logD

4.812

Water Solubility, LogSw

-4.90

Polar Surface Area

33.058

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

6.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

E014-0015 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E014-0015 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E014-0015?
Check Price and Availability of E014-0015, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E014-0015 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E014-0015
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E014-0015
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E014-0015 available by request