E016-2608 Screening compound: 2-(4-ethylphenyl)-7-methyl-5-[2-(morpholin-4-yl)-2-oxoethyl]-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

E016-2608 Screening compound: 2-(4-ethylphenyl)-7-methyl-5-[2-(morpholin-4-yl)-2-oxoethyl]-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one
E016-2608 Screening compound: 2-(4-ethylphenyl)-7-methyl-5-[2-(morpholin-4-yl)-2-oxoethyl]-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E016-2608
2-(4-ethylphenyl)-7-methyl-5-[2-(morpholin-4-yl)-2-oxoethyl]-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E016-2608

Molecular Formula

C20H23N5O3 (C20 H23 N5 O3)

Compound Name

2-(4-ethylphenyl)-7-methyl-5-[2-(morpholin-4-yl)-2-oxoethyl]-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

IUPAC name

2-(4-ethylphenyl)-7-methyl-5-[2-(morpholin-4-yl)-2-oxoethyl]-4H5H-pyrazolo[15-d][124]triazin-4-one

SMILES

CCc(cc1)ccc1-c(cc12)nn1C(C)=NN(CC(N1CCOCC1)=O)C2=O

InChI

InChI=1S/C20H23N5O3/c1-3-15-4-6-16(7-5-15)17-12-18-20(27)24(21-14(2)25(18)22-17)13-19(26)23-8-10-28-11-9-23/h4-7,12H,3,8-11,13H2,1-2H3

InChI Key

RUQFANFJEKUXBZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14838778

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.993

Distribution Coefficient, logD

1.993

Water Solubility, LogSw

-2.33

Polar Surface Area

65.067

Acid Dissociation Constant (pKa)

17.24

Base Dissociation Constant (pKb)

1.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

E016-2608 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

PI3K-Targeted Library (17255 compounds)

Purinergic Library (3321 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • Kinases
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E016-2608 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E016-2608?
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What is the minimum amount of E016-2608 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E016-2608
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E016-2608
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E016-2608 available by request