E018-1808 Screening compound: N-[3-(diethylamino)propyl]-6-methoxy-3-(phenylsulfanyl)-1H-indole-2-carboxamide

E018-1808 Screening compound: N-[3-(diethylamino)propyl]-6-methoxy-3-(phenylsulfanyl)-1H-indole-2-carboxamide
E018-1808 Screening compound: N-[3-(diethylamino)propyl]-6-methoxy-3-(phenylsulfanyl)-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-1808
N-[3-(diethylamino)propyl]-6-methoxy-3-(phenylsulfanyl)-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-1808

Molecular Formula

C23H29N3O2S (C23 H29 N3 O2 S)

Compound Name

N-[3-(diethylamino)propyl]-6-methoxy-3-(phenylsulfanyl)-1H-indole-2-carboxamide

IUPAC name

N-[3-(diethylamino)propyl]-6-methoxy-3-(phenylsulfanyl)-1H-indole-2-carboxamide

SMILES

CCN(CC)CCCNC(c([nH]c1c2ccc(OC)c1)c2Sc1ccccc1)=O

InChI

InChI=1S/C23H29N3O2S/c1-4-26(5-2)15-9-14-24-23(27)21-22(29-18-10-7-6-8-11-18)19-13-12-17(28-3)16-20(19)25-21/h6-8,10-13,16,25H,4-5,9,14-15H2,1-3H3,(H,24,27)

InChI Key

WCVOOBSCYLSRMJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14839350

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.264

Distribution Coefficient, logD

1.543

Water Solubility, LogSw

-4.15

Polar Surface Area

45.568

Acid Dissociation Constant (pKa)

15.88

Base Dissociation Constant (pKb)

10.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

E018-1808 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-1808 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-1808?
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What is the minimum amount of E018-1808 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-1808
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-1808
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-1808 available by request