E018-2371 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-N-[2-(diethylamino)ethyl]-6-methoxy-1H-indole-2-carboxamide

E018-2371 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-N-[2-(diethylamino)ethyl]-6-methoxy-1H-indole-2-carboxamide
E018-2371 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-N-[2-(diethylamino)ethyl]-6-methoxy-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-2371
3-[(4-chlorophenyl)sulfanyl]-N-[2-(diethylamino)ethyl]-6-methoxy-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-2371

Molecular Formula

C22H26ClN3O2S (C22 H26 ClN3 O2 S)

Compound Name

3-[(4-chlorophenyl)sulfanyl]-N-[2-(diethylamino)ethyl]-6-methoxy-1H-indole-2-carboxamide

IUPAC name

3-[(4-chlorophenyl)sulfanyl]-N-[2-(diethylamino)ethyl]-6-methoxy-1H-indole-2-carboxamide

SMILES

CCN(CC)CCNC(c([nH]c1c2ccc(OC)c1)c2Sc(cc1)ccc1Cl)=O

InChI

InChI=1S/C22H26ClN3O2S/c1-4-26(5-2)13-12-24-22(27)20-21(29-17-9-6-15(23)7-10-17)18-11-8-16(28-3)14-19(18)25-20/h6-11,14,25H,4-5,12-13H2,1-3H3,(H,24,27)

InChI Key

WHGUCFZXADPAMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14839467

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.99

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.921

Distribution Coefficient, logD

3.492

Water Solubility, LogSw

-4.88

Polar Surface Area

45.568

Acid Dissociation Constant (pKa)

14.16

Base Dissociation Constant (pKb)

8.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

E018-2371 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-2371 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-2371?
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What is the minimum amount of E018-2371 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-2371
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-2371
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-2371 available by request