E130-0669 Screening compound: ethyl 4-[4-(3-chlorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-yl]piperazine-1-carboxylate

E130-0669 Screening compound: ethyl 4-[4-(3-chlorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-yl]piperazine-1-carboxylate
E130-0669 Screening compound: ethyl 4-[4-(3-chlorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-yl]piperazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E130-0669
ethyl 4-[4-(3-chlorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-yl]piperazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E130-0669

Molecular Formula

C24H23ClN4O3 (C24 H23 ClN4 O3)

Compound Name

ethyl 4-[4-(3-chlorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-yl]piperazine-1-carboxylate

IUPAC name

ethyl 4-[4-(3-chlorophenyl)-5H-chromeno[43-d]pyrimidin-2-yl]piperazine-1-carboxylate

SMILES

CCOC(N(CC1)CCN1c1nc(-c(cccc2)c2OC2)c2c(-c2cccc(Cl)c2)n1)=O

InChI

InChI=1S/C24H23ClN4O3/c1-2-31-24(30)29-12-10-28(11-13-29)23-26-21(16-6-5-7-17(25)14-16)19-15-32-20-9-4-3-8-18(20)22(19)27-23/h3-9,14H,2,10-13,15H2,1H3

InChI Key

FNRTZPXILGHQCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14840800

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.639

Distribution Coefficient, logD

5.639

Water Solubility, LogSw

-5.84

Polar Surface Area

53.428

Acid Dissociation Constant (pKa)

16.68

Base Dissociation Constant (pKb)

4.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

E130-0669 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E130-0669 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E130-0669?
Check Price and Availability of E130-0669, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E130-0669 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E130-0669
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E130-0669
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E130-0669 available by request