E144-0835 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

E144-0835 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide
E144-0835 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E144-0835
N-[2-(4-chlorophenyl)ethyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E144-0835

Molecular Formula

C16H18BrClN4O3S (C16 H18 BrClN4 O3 S)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

SMILES

CN(CC(NCCc(cc1)ccc1Cl)=O)S(c1cc(Br)cnc1N)(=O)=O

InChI

InChI=1S/C16H18BrClN4O3S/c1-22(26(24,25)14-8-12(17)9-21-16(14)19)10-15(23)20-7-6-11-2-4-13(18)5-3-11/h2-5,8-9H,6-7,10H2,1H3,(H2,19,21)(H,20,23)

InChI Key

QSEAGVIXJXHSKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842366

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.77

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.862

Distribution Coefficient, logD

1.862

Water Solubility, LogSw

-3.01

Polar Surface Area

86.950

Acid Dissociation Constant (pKa)

13.69

Base Dissociation Constant (pKb)

-1.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

E144-0835 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E144-0835 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E144-0835?
Check Price and Availability of E144-0835, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E144-0835 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E144-0835
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E144-0835
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E144-0835 available by request