E144-0862 Screening compound: N-[(4-methoxyphenyl)methyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

E144-0862 Screening compound: N-[(4-methoxyphenyl)methyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide
E144-0862 Screening compound: N-[(4-methoxyphenyl)methyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E144-0862
N-[(4-methoxyphenyl)methyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E144-0862

Molecular Formula

C16H19BrN4O4S (C16 H19 BrN4 O4 S)

Compound Name

N-[(4-methoxyphenyl)methyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

IUPAC name

N-[(4-methoxyphenyl)methyl]-2-(N-methyl2-amino-5-bromopyridine-3-sulfonamido)acetamide

SMILES

CN(CC(NCc(cc1)ccc1OC)=O)S(c1cc(Br)cnc1N)(=O)=O

InChI

InChI=1S/C16H19BrN4O4S/c1-21(26(23,24)14-7-12(17)9-20-16(14)18)10-15(22)19-8-11-3-5-13(25-2)6-4-11/h3-7,9H,8,10H2,1-2H3,(H2,18,20)(H,19,22)

InChI Key

SBZRAXHAIGTVPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842372

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.32

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.475

Distribution Coefficient, logD

1.475

Water Solubility, LogSw

-2.64

Polar Surface Area

94.652

Acid Dissociation Constant (pKa)

13.32

Base Dissociation Constant (pKb)

-1.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

E144-0862 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E144-0862 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E144-0862?
Check Price and Availability of E144-0862, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E144-0862 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E144-0862
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E144-0862
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E144-0862 available by request