E146-0251 Screening compound: 1-{4H-CHROMENO[3,4-D][1,2]OXAZOLE-3-CARBONYL}PYRROLIDINE

E146-0251 Screening compound: 1-{4H-CHROMENO[3,4-D][1,2]OXAZOLE-3-CARBONYL}PYRROLIDINE
E146-0251 Screening compound: 1-{4H-CHROMENO[3,4-D][1,2]OXAZOLE-3-CARBONYL}PYRROLIDINE alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-0251
1-{4H-CHROMENO[3,4-D][1,2]OXAZOLE-3-CARBONYL}PYRROLIDINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-0251

Molecular Formula

C15H14N2O3 (C15 H14 N2 O3)

Compound Name

1-{4H-CHROMENO[3,4-D][1,2]OXAZOLE-3-CARBONYL}PYRROLIDINE

IUPAC name

n/a

SMILES

O=C(c1noc-2c1COc1c2cccc1)N1CCCC1

InChI

InChI=1S/C15H14N2O3/c18-15(17-7-3-4-8-17)13-11-9-19-12-6-2-1-5-10(12)14(11)20-16-13/h1-2,5-6H,3-4,7-9H2

InChI Key

BITMZUCDBNSNJH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597711

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

270.29

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.232

Distribution Coefficient, logD

2.232

Water Solubility, LogSw

-2.70

Polar Surface Area

47.783

Acid Dissociation Constant (pKa)

19.32

Base Dissociation Constant (pKb)

-3.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E146-0251 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

Soluble Diversity Library (15920 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E146-0251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-0251?
Check Price and Availability of E146-0251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-0251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-0251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-0251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-0251 available by request