E146-1188 Screening compound: 1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

E146-1188 Screening compound: 1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine
E146-1188 Screening compound: 1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1188
1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1188

Molecular Formula

C17H19N3O2 (C17 H19 N3 O2)

Compound Name

1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

IUPAC name

1-{1-methyl-1H4H-chromeno[43-c]pyrazole-3-carbonyl}piperidine

SMILES

Cn1nc(C(N2CCCCC2)=O)c2c1-c(cccc1)c1OC2

InChI

InChI=1S/C17H19N3O2/c1-19-16-12-7-3-4-8-14(12)22-11-13(16)15(18-19)17(21)20-9-5-2-6-10-20/h3-4,7-8H,2,5-6,9-11H2,1H3

InChI Key

NAQFYPOHCDGTFY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

297.36

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.042

Distribution Coefficient, logD

2.042

Water Solubility, LogSw

-2.55

Polar Surface Area

39.659

Acid Dissociation Constant (pKa)

19.18

Base Dissociation Constant (pKb)

-1.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

E146-1188 in Drug Discovery

Included in Screening Libraries

Fragments Library (11262 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Therapeutical areas:
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic

References: we are preparing a list of scientific research reports with E146-1188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1188?
Check Price and Availability of E146-1188, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1188 available by request