E146-1322 Screening compound: 1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}-2,3-dihydro-1H-indole

E146-1322 Screening compound: 1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}-2,3-dihydro-1H-indole
E146-1322 Screening compound: 1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1322
1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1322

Molecular Formula

C20H17N3O2 (C20 H17 N3 O2)

Compound Name

1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}-2,3-dihydro-1H-indole

IUPAC name

1-{1-methyl-1H4H-chromeno[43-c]pyrazole-3-carbonyl}-23-dihydro-1H-indole

SMILES

Cn1nc(C(N(CC2)c3c2cccc3)=O)c2c1-c(cccc1)c1OC2

InChI

InChI=1S/C20H17N3O2/c1-22-19-14-7-3-5-9-17(14)25-12-15(19)18(21-22)20(24)23-11-10-13-6-2-4-8-16(13)23/h2-9H,10-12H2,1H3

InChI Key

QBEFEKPWPCGJQV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14843065

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

331.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.866

Distribution Coefficient, logD

2.866

Water Solubility, LogSw

-3.55

Polar Surface Area

38.690

Acid Dissociation Constant (pKa)

19.18

Base Dissociation Constant (pKb)

-1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

E146-1322 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Therapeutical areas:
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic

References: we are preparing a list of scientific research reports with E146-1322 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1322?
Check Price and Availability of E146-1322, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1322 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1322
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1322
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1322 available by request