E153-0137 Screening compound: N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)cyclopropanecarboxamide

E153-0137 Screening compound: N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)cyclopropanecarboxamide
E153-0137 Screening compound: N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E153-0137
N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E153-0137

Molecular Formula

C16H13N3OS (C16 H13 N3 OS)

Compound Name

N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)cyclopropanecarboxamide

IUPAC name

N-(3-{[13]thiazolo[54-b]pyridin-2-yl}phenyl)cyclopropanecarboxamide

SMILES

O=C(C1CC1)Nc1cccc(-c2nc3cccnc3s2)c1

InChI

InChI=1S/C16H13N3OS/c20-14(10-6-7-10)18-12-4-1-3-11(9-12)15-19-13-5-2-8-17-16(13)21-15/h1-5,8-10H,6-7H2,(H,18,20)

InChI Key

NCVXZEOCORADHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05894407

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

295.36

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.654

Distribution Coefficient, logD

3.654

Water Solubility, LogSw

-4.03

Polar Surface Area

42.707

Acid Dissociation Constant (pKa)

13.22

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

E153-0137 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

BRD4 Targeted Library (4534 compounds)

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Others

References: we are preparing a list of scientific research reports with E153-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E153-0137?
Check Price and Availability of E153-0137, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E153-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E153-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E153-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E153-0137 available by request