E155-0349 Screening compound: N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(pyridin-3-yl)ethyl}-2-methylpropanamide

E155-0349 Screening compound: N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(pyridin-3-yl)ethyl}-2-methylpropanamide
E155-0349 Screening compound: N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(pyridin-3-yl)ethyl}-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E155-0349
N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(pyridin-3-yl)ethyl}-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E155-0349

Molecular Formula

C21H27FN4O (C21 H27 FN4 O)

Compound Name

N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(pyridin-3-yl)ethyl}-2-methylpropanamide

IUPAC name

N-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-(pyridin-3-yl)ethyl}-2-methylpropanamide

SMILES

CC(C)C(NCC(c1cnccc1)N(CC1)CCN1c(cccc1)c1F)=O

InChI

InChI=1S/C21H27FN4O/c1-16(2)21(27)24-15-20(17-6-5-9-23-14-17)26-12-10-25(11-13-26)19-8-4-3-7-18(19)22/h3-9,14,16,20H,10-13,15H2,1-2H3,(H,24,27)/t20-/m0/s1

InChI Key

LXFICDWYOPWBLC-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD05894189

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.443

Distribution Coefficient, logD

2.441

Water Solubility, LogSw

-2.15

Polar Surface Area

40.390

Acid Dissociation Constant (pKa)

13.14

Base Dissociation Constant (pKb)

4.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

E155-0349 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system

References: we are preparing a list of scientific research reports with E155-0349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E155-0349?
Check Price and Availability of E155-0349, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E155-0349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E155-0349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E155-0349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E155-0349 available by request