E157-1008 Screening compound: 3,4-dimethoxy-N-[5-(morpholine-4-sulfonyl)-1,3,4-thiadiazol-2-yl]benzamide

E157-1008 Screening compound: 3,4-dimethoxy-N-[5-(morpholine-4-sulfonyl)-1,3,4-thiadiazol-2-yl]benzamide
E157-1008 Screening compound: 3,4-dimethoxy-N-[5-(morpholine-4-sulfonyl)-1,3,4-thiadiazol-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-1008
3,4-dimethoxy-N-[5-(morpholine-4-sulfonyl)-1,3,4-thiadiazol-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-1008

Molecular Formula

C15H18N4O6S2 (C15 H18 N4 O6 S2)

Compound Name

3,4-dimethoxy-N-[5-(morpholine-4-sulfonyl)-1,3,4-thiadiazol-2-yl]benzamide

IUPAC name

34-dimethoxy-N-[5-(morpholine-4-sulfonyl)-134-thiadiazol-2-yl]benzamide

SMILES

COc(ccc(C(Nc(s1)nnc1S(N1CCOCC1)(=O)=O)=O)c1)c1OC

InChI

InChI=1S/C15H18N4O6S2/c1-23-11-4-3-10(9-12(11)24-2)13(20)16-14-17-18-15(26-14)27(21,22)19-5-7-25-8-6-19/h3-4,9H,5-8H2,1-2H3,(H,16,17,20)

InChI Key

RRZZLDJICWWEHD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14843497

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.46

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.328

Distribution Coefficient, logD

0.557

Water Solubility, LogSw

-2.43

Polar Surface Area

101.530

Acid Dissociation Constant (pKa)

6.71

Base Dissociation Constant (pKb)

-7.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

E157-1008 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E157-1008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-1008?
Check Price and Availability of E157-1008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-1008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-1008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-1008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-1008 available by request