E157-8183 Screening compound: N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide

E157-8183 Screening compound: N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide
E157-8183 Screening compound: N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-8183
N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-8183

Molecular Formula

C15H20N4O4S2 (C15 H20 N4 O4 S2)

Compound Name

N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide

IUPAC name

N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-134-thiadiazol-2-yl)cyclohexanecarboxamide

SMILES

CN(Cc1ccco1)S(c1nnc(NC(C2CCCCC2)=O)s1)(=O)=O

InChI

InChI=1S/C15H20N4O4S2/c1-19(10-12-8-5-9-23-12)25(21,22)15-18-17-14(24-15)16-13(20)11-6-3-2-4-7-11/h5,8-9,11H,2-4,6-7,10H2,1H3,(H,16,17,20)

InChI Key

XPFZURCJCRXIJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844404

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.48

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.021

Distribution Coefficient, logD

2.211

Water Solubility, LogSw

-3.32

Polar Surface Area

87.155

Acid Dissociation Constant (pKa)

6.66

Base Dissociation Constant (pKb)

-6.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

53.30

E157-8183 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E157-8183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-8183?
Check Price and Availability of E157-8183, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-8183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-8183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-8183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-8183 available by request