E157-8368 Screening compound: N-{5-[(4-chlorophenyl)(ethyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide

E157-8368 Screening compound: N-{5-[(4-chlorophenyl)(ethyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide
E157-8368 Screening compound: N-{5-[(4-chlorophenyl)(ethyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-8368
N-{5-[(4-chlorophenyl)(ethyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-8368

Molecular Formula

C19H19ClN4O5S2 (C19 H19 ClN4 O5 S2)

Compound Name

N-{5-[(4-chlorophenyl)(ethyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}-3,4-dimethoxybenzamide

IUPAC name

N-{5-[(4-chlorophenyl)(ethyl)sulfamoyl]-134-thiadiazol-2-yl}-34-dimethoxybenzamide

SMILES

CCN(c(cc1)ccc1Cl)S(c1nnc(NC(c(cc2)cc(OC)c2OC)=O)s1)(=O)=O

InChI

InChI=1S/C19H19ClN4O5S2/c1-4-24(14-8-6-13(20)7-9-14)31(26,27)19-23-22-18(30-19)21-17(25)12-5-10-15(28-2)16(11-12)29-3/h5-11H,4H2,1-3H3,(H,21,22,25)

InChI Key

WWHHTSNWOFJNJE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844412

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.97

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.936

Distribution Coefficient, logD

3.353

Water Solubility, LogSw

-4.53

Polar Surface Area

93.460

Acid Dissociation Constant (pKa)

6.95

Base Dissociation Constant (pKb)

-8.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

E157-8368 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E157-8368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-8368?
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What is the minimum amount of E157-8368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-8368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-8368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-8368 available by request