E203-1496 Screening compound: 1,3,3-trimethyl-5-{[3-(4-methylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-2-one

E203-1496 Screening compound: 1,3,3-trimethyl-5-{[3-(4-methylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-2-one
E203-1496 Screening compound: 1,3,3-trimethyl-5-{[3-(4-methylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E203-1496
1,3,3-trimethyl-5-{[3-(4-methylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E203-1496

Molecular Formula

C23H33N3O4S (C23 H33 N3 O4 S)

Compound Name

1,3,3-trimethyl-5-{[3-(4-methylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-2-one

IUPAC name

133-trimethyl-5-{[3-(4-methylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-23-dihydro-1H-indol-2-one

SMILES

CC(CC1)CCN1C(C(CCC1)CN1S(c(cc1)cc(C2(C)C)c1N(C)C2=O)(=O)=O)=O

InChI

InChI=1S/C23H33N3O4S/c1-16-9-12-25(13-10-16)21(27)17-6-5-11-26(15-17)31(29,30)18-7-8-20-19(14-18)23(2,3)22(28)24(20)4/h7-8,14,16-17H,5-6,9-13,15H2,1-4H3/t17-/m0/s1

InChI Key

RQELDFLUQWRXKC-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD14845668

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.568

Distribution Coefficient, logD

2.568

Water Solubility, LogSw

-3.09

Polar Surface Area

64.037

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

-0.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

65.20

E203-1496 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

GPCR Targeted Library (31838 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E203-1496 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E203-1496?
Check Price and Availability of E203-1496, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E203-1496 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E203-1496
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E203-1496
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E203-1496 available by request