E207-0757 Screening compound: 1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-(5-methyl-1,2-benzoxazol-3-yl)ethan-1-one

E207-0757 Screening compound: 1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-(5-methyl-1,2-benzoxazol-3-yl)ethan-1-one
E207-0757 Screening compound: 1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-(5-methyl-1,2-benzoxazol-3-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E207-0757
1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-(5-methyl-1,2-benzoxazol-3-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E207-0757

Molecular Formula

C21H22ClN3O2 (C21 H22 ClN3 O2)

Compound Name

1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-(5-methyl-1,2-benzoxazol-3-yl)ethan-1-one

IUPAC name

1-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-2-(5-methyl-12-benzoxazol-3-yl)ethan-1-one

SMILES

Cc(cc1)cc2c1onc2CC(N(CC1)CCN1c1c(C)ccc(Cl)c1)=O

InChI

InChI=1S/C21H22ClN3O2/c1-14-3-6-20-17(11-14)18(23-27-20)13-21(26)25-9-7-24(8-10-25)19-12-16(22)5-4-15(19)2/h3-6,11-12H,7-10,13H2,1-2H3

InChI Key

CYBFFEPNBGAGDW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14846241

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.743

Distribution Coefficient, logD

4.743

Water Solubility, LogSw

-4.71

Polar Surface Area

42.013

Acid Dissociation Constant (pKa)

20.69

Base Dissociation Constant (pKb)

3.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E207-0757 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS targets activity set (6557 compounds)

Human Receptors Annotated Library (5376 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E207-0757 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E207-0757?
Check Price and Availability of E207-0757, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E207-0757 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E207-0757
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E207-0757
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E207-0757 available by request