E214-0039 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonamide

E214-0039 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonamide
E214-0039 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E214-0039
N-(5-chloro-2,4-dimethoxyphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E214-0039

Molecular Formula

C13H14ClN3O6S (C13 H14 ClN3 O6 S)

Compound Name

N-(5-chloro-2,4-dimethoxyphenyl)-6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonamide

IUPAC name

N-(5-chloro-24-dimethoxyphenyl)-6-methyl-24-dioxo-1234-tetrahydropyrimidine-5-sulfonamide

SMILES

CC(NC(NC1=O)=O)=C1S(Nc(c(OC)c1)cc(Cl)c1OC)(=O)=O

InChI

InChI=1S/C13H14ClN3O6S/c1-6-11(12(18)16-13(19)15-6)24(20,21)17-8-4-7(14)9(22-2)5-10(8)23-3/h4-5,17H,1-3H3,(H2,15,16,18,19)

InChI Key

ZVWPAMZFGOAAQW-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.79

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.990

Distribution Coefficient, logD

-3.794

Water Solubility, LogSw

-2.69

Polar Surface Area

103.985

Acid Dissociation Constant (pKa)

2.62

Base Dissociation Constant (pKb)

-7.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.08

E214-0039 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E214-0039 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E214-0039?
Check Price and Availability of E214-0039, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E214-0039 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E214-0039
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E214-0039
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E214-0039 available by request