E228-1792 Screening compound: 7-fluoro-5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one

E228-1792 Screening compound: 7-fluoro-5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one
E228-1792 Screening compound: 7-fluoro-5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-1792
7-fluoro-5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-1792

Molecular Formula

C22H20FN5O2 (C22 H20 FN5 O2)

Compound Name

7-fluoro-5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H,5H-pyrrolo[1,2-a]quinoxalin-4-one

IUPAC name

7-fluoro-5-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}-4H5H-pyrrolo[12-a]quinoxalin-4-one

SMILES

O=C(CN(c(cc(cc1)F)c1-n1c2ccc1)C2=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C22H20FN5O2/c23-16-6-7-17-19(14-16)28(22(30)18-4-3-9-27(17)18)15-21(29)26-12-10-25(11-13-26)20-5-1-2-8-24-20/h1-9,14H,10-13,15H2

InChI Key

IUHKRZZFKPCVNB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850045

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.684

Distribution Coefficient, logD

2.675

Water Solubility, LogSw

-2.95

Polar Surface Area

45.130

Acid Dissociation Constant (pKa)

22.47

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

E228-1792 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with E228-1792 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-1792?
Check Price and Availability of E228-1792, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-1792 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-1792
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-1792
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-1792 available by request