E228-2493 Screening compound: N-[2-(3,4-diethoxyphenyl)ethyl]-3-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}propanamide

E228-2493 Screening compound: N-[2-(3,4-diethoxyphenyl)ethyl]-3-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}propanamide
E228-2493 Screening compound: N-[2-(3,4-diethoxyphenyl)ethyl]-3-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-2493
N-[2-(3,4-diethoxyphenyl)ethyl]-3-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-2493

Molecular Formula

C26H28FN3O4 (C26 H28 FN3 O4)

Compound Name

N-[2-(3,4-diethoxyphenyl)ethyl]-3-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}propanamide

IUPAC name

N-[2-(34-diethoxyphenyl)ethyl]-3-{7-fluoro-4-oxo-4H5H-pyrrolo[12-a]quinoxalin-5-yl}propanamide

SMILES

CCOc(ccc(CCNC(CCN(c(cc(cc1)F)c1-n1c2ccc1)C2=O)=O)c1)c1OCC

InChI

InChI=1S/C26H28FN3O4/c1-3-33-23-10-7-18(16-24(23)34-4-2)11-13-28-25(31)12-15-30-22-17-19(27)8-9-20(22)29-14-5-6-21(29)26(30)32/h5-10,14,16-17H,3-4,11-13,15H2,1-2H3,(H,28,31)

InChI Key

DRFWWKFZZIOMNO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850095

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.013

Distribution Coefficient, logD

3.013

Water Solubility, LogSw

-3.31

Polar Surface Area

55.677

Acid Dissociation Constant (pKa)

13.77

Base Dissociation Constant (pKb)

-0.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

E228-2493 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with E228-2493 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-2493?
Check Price and Availability of E228-2493, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-2493 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-2493
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-2493
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-2493 available by request