E228-2784 Screening compound: N-(2,5-diethoxyphenyl)-4-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide

E228-2784 Screening compound: N-(2,5-diethoxyphenyl)-4-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide
E228-2784 Screening compound: N-(2,5-diethoxyphenyl)-4-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E228-2784
N-(2,5-diethoxyphenyl)-4-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E228-2784

Molecular Formula

C25H26FN3O4 (C25 H26 FN3 O4)

Compound Name

N-(2,5-diethoxyphenyl)-4-{7-fluoro-4-oxo-4H,5H-pyrrolo[1,2-a]quinoxalin-5-yl}butanamide

IUPAC name

N-(25-diethoxyphenyl)-4-{7-fluoro-4-oxo-4H5H-pyrrolo[12-a]quinoxalin-5-yl}butanamide

SMILES

CCOc(cc1)cc(NC(CCCN(c(cc(cc2)F)c2-n2c3ccc2)C3=O)=O)c1OCC

InChI

InChI=1S/C25H26FN3O4/c1-3-32-18-10-12-23(33-4-2)19(16-18)27-24(30)8-6-14-29-22-15-17(26)9-11-20(22)28-13-5-7-21(28)25(29)31/h5,7,9-13,15-16H,3-4,6,8,14H2,1-2H3,(H,27,30)

InChI Key

SKQZMSTYGGGAQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850198

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.769

Distribution Coefficient, logD

3.768

Water Solubility, LogSw

-3.85

Polar Surface Area

53.729

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

2.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

E228-2784 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with E228-2784 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E228-2784?
Check Price and Availability of E228-2784, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E228-2784 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E228-2784
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E228-2784
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E228-2784 available by request