E229-0376 Screening compound: N-[2-(4-chlorophenyl)ethyl]-1-{pyrrolo[1,2-a]quinoxalin-4-yl}piperidine-3-carboxamide

E229-0376 Screening compound: N-[2-(4-chlorophenyl)ethyl]-1-{pyrrolo[1,2-a]quinoxalin-4-yl}piperidine-3-carboxamide
E229-0376 Screening compound: N-[2-(4-chlorophenyl)ethyl]-1-{pyrrolo[1,2-a]quinoxalin-4-yl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E229-0376
N-[2-(4-chlorophenyl)ethyl]-1-{pyrrolo[1,2-a]quinoxalin-4-yl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E229-0376

Molecular Formula

C25H25ClN4O (C25 H25 ClN4 O)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-1-{pyrrolo[1,2-a]quinoxalin-4-yl}piperidine-3-carboxamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-1-{pyrrolo[12-a]quinoxalin-4-yl}piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1nc(cccc2)c2n2c1ccc2)NCCc(cc1)ccc1Cl

InChI

InChI=1S/C25H25ClN4O/c26-20-11-9-18(10-12-20)13-14-27-25(31)19-5-3-15-29(17-19)24-23-8-4-16-30(23)22-7-2-1-6-21(22)28-24/h1-2,4,6-12,16,19H,3,5,13-15,17H2,(H,27,31)/t19-/m0/s1

InChI Key

ZHXPJKTVQLMWIJ-IBGZPJMESA-N

MDL Number (MFCD)

MFCD14850448

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.95

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.727

Distribution Coefficient, logD

4.716

Water Solubility, LogSw

-4.93

Polar Surface Area

35.347

Acid Dissociation Constant (pKa)

13.73

Base Dissociation Constant (pKb)

5.79

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.00

E229-0376 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E229-0376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E229-0376?
Check Price and Availability of E229-0376, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E229-0376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E229-0376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E229-0376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E229-0376 available by request