E233-1638 Screening compound: 1-{2-[(4-chlorophenyl)methyl]-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carbonyl}-4-cyclohexylpiperazine

E233-1638 Screening compound: 1-{2-[(4-chlorophenyl)methyl]-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carbonyl}-4-cyclohexylpiperazine
E233-1638 Screening compound: 1-{2-[(4-chlorophenyl)methyl]-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carbonyl}-4-cyclohexylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E233-1638
1-{2-[(4-chlorophenyl)methyl]-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carbonyl}-4-cyclohexylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E233-1638

Molecular Formula

C28H33ClN4O2 (C28 H33 ClN4 O2)

Compound Name

1-{2-[(4-chlorophenyl)methyl]-8-methyl-2H,4H,5H-furo[2,3-g]indazole-7-carbonyl}-4-cyclohexylpiperazine

IUPAC name

1-{2-[(4-chlorophenyl)methyl]-8-methyl-2H4H5H-furo[23-g]indazole-7-carbonyl}-4-cyclohexylpiperazine

SMILES

Cc1c(C(N(CC2)CCN2C2CCCCC2)=O)oc2c1-c1nn(Cc(cc3)ccc3Cl)cc1CC2

InChI

InChI=1S/C28H33ClN4O2/c1-19-25-24(12-9-21-18-33(30-26(21)25)17-20-7-10-22(29)11-8-20)35-27(19)28(34)32-15-13-31(14-16-32)23-5-3-2-4-6-23/h7-8,10-11,18,23H,2-6,9,12-17H2,1H3

InChI Key

NNJCXOUAFVYZBX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850647

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.05

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.081

Distribution Coefficient, logD

4.922

Water Solubility, LogSw

-5.55

Polar Surface Area

43.578

Acid Dissociation Constant (pKa)

21.84

Base Dissociation Constant (pKb)

7.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

E233-1638 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E233-1638 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E233-1638?
Check Price and Availability of E233-1638, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E233-1638 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E233-1638
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E233-1638
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E233-1638 available by request