E233-1964 Screening compound: ethyl 4-({[2-(2-chlorobenzyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazol-7-yl]carbonyl}amino)benzoate

E233-1964 Screening compound: ethyl 4-({[2-(2-chlorobenzyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazol-7-yl]carbonyl}amino)benzoate
E233-1964 Screening compound: ethyl 4-({[2-(2-chlorobenzyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazol-7-yl]carbonyl}amino)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E233-1964
ethyl 4-({[2-(2-chlorobenzyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazol-7-yl]carbonyl}amino)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E233-1964

Molecular Formula

C27H24ClN3O4 (C27 H24 ClN3 O4)

Compound Name

ethyl 4-({[2-(2-chlorobenzyl)-8-methyl-4,5-dihydro-2H-furo[2,3-g]indazol-7-yl]carbonyl}amino)benzoate

IUPAC name

ethyl 4-{2-[(2-chlorophenyl)methyl]-8-methyl-2H4H5H-furo[23-g]indazole-7-amido}benzoate

SMILES

CCOC(c(cc1)ccc1NC(c1c(C)c(-c2nn(Cc(cccc3)c3Cl)cc2CC2)c2o1)=O)=O

InChI

InChI=1S/C27H24ClN3O4/c1-3-34-27(33)17-8-11-20(12-9-17)29-26(32)25-16(2)23-22(35-25)13-10-19-15-31(30-24(19)23)14-18-6-4-5-7-21(18)28/h4-9,11-12,15H,3,10,13-14H2,1-2H3,(H,29,32)

InChI Key

ZVYKGDKHYYYGKF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14850708

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.96

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.824

Distribution Coefficient, logD

5.823

Water Solubility, LogSw

-6.11

Polar Surface Area

67.681

Acid Dissociation Constant (pKa)

10.10

Base Dissociation Constant (pKb)

-0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.22

E233-1964 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Proteases Annotated Library (2868 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E233-1964 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E233-1964?
Check Price and Availability of E233-1964, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E233-1964 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E233-1964
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E233-1964
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E233-1964 available by request