E243-0118 Screening compound: 3-[2-(4-methoxyphenyl)-2-oxoethyl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one

E243-0118 Screening compound: 3-[2-(4-methoxyphenyl)-2-oxoethyl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one
E243-0118 Screening compound: 3-[2-(4-methoxyphenyl)-2-oxoethyl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E243-0118
3-[2-(4-methoxyphenyl)-2-oxoethyl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E243-0118

Molecular Formula

C19H14N2O4 (C19 H14 N2 O4)

Compound Name

3-[2-(4-methoxyphenyl)-2-oxoethyl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one

IUPAC name

5-[2-(4-methoxyphenyl)-2-oxoethyl]-8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)31012-pentaen-6-one

SMILES

COc(cc1)ccc1C(CN(C=Nc1c2oc3c1cccc3)C2=O)=O

InChI

InChI=1S/C19H14N2O4/c1-24-13-8-6-12(7-9-13)15(22)10-21-11-20-17-14-4-2-3-5-16(14)25-18(17)19(21)23/h2-9,11H,10H2,1H3

InChI Key

SZLNESRDGLSOKL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05910672

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

334.33

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.715

Distribution Coefficient, logD

2.715

Water Solubility, LogSw

-2.99

Polar Surface Area

53.025

Acid Dissociation Constant (pKa)

24.62

Base Dissociation Constant (pKb)

-0.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

E243-0118 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E243-0118 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E243-0118?
Check Price and Availability of E243-0118, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E243-0118 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E243-0118
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E243-0118
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E243-0118 available by request