E466-0024 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-{4H-chromeno[3,4-d][1,2]oxazol-3-yl}urea

E466-0024 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-{4H-chromeno[3,4-d][1,2]oxazol-3-yl}urea
E466-0024 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-{4H-chromeno[3,4-d][1,2]oxazol-3-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E466-0024
1-(5-chloro-2,4-dimethoxyphenyl)-3-{4H-chromeno[3,4-d][1,2]oxazol-3-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E466-0024

Molecular Formula

C19H16ClN3O5 (C19 H16 ClN3 O5)

Compound Name

1-(5-chloro-2,4-dimethoxyphenyl)-3-{4H-chromeno[3,4-d][1,2]oxazol-3-yl}urea

IUPAC name

1-(5-chloro-24-dimethoxyphenyl)-3-{4H-chromeno[34-d][12]oxazol-3-yl}urea

SMILES

COc(c(NC(Nc1noc-2c1COc1c2cccc1)=O)c1)cc(OC)c1Cl

InChI

InChI=1S/C19H16ClN3O5/c1-25-15-8-16(26-2)13(7-12(15)20)21-19(24)22-18-11-9-27-14-6-4-3-5-10(14)17(11)28-23-18/h3-8H,9H2,1-2H3,(H2,21,22,23,24)

InChI Key

ZMOHKTJHLHIGCU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14854540

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.81

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.108

Distribution Coefficient, logD

4.103

Water Solubility, LogSw

-4.45

Polar Surface Area

77.504

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

1.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

E466-0024 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E466-0024 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E466-0024?
Check Price and Availability of E466-0024, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E466-0024 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E466-0024
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E466-0024
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E466-0024 available by request