E475-0267 Screening compound: 11-oxo-N-[4-(piperidine-1-sulfonyl)phenyl]-6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide

E475-0267 Screening compound: 11-oxo-N-[4-(piperidine-1-sulfonyl)phenyl]-6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide
E475-0267 Screening compound: 11-oxo-N-[4-(piperidine-1-sulfonyl)phenyl]-6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E475-0267
11-oxo-N-[4-(piperidine-1-sulfonyl)phenyl]-6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E475-0267

Molecular Formula

C24H26N4O4S (C24 H26 N4 O4 S)

Compound Name

11-oxo-N-[4-(piperidine-1-sulfonyl)phenyl]-6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide

IUPAC name

11-oxo-N-[4-(piperidine-1-sulfonyl)phenyl]-6H7H8H9H11H-pyrido[21-b]quinazoline-3-carboxamide

SMILES

O=C(c(cc1)cc(N=C2N3CCCC2)c1C3=O)Nc(cc1)ccc1S(N1CCCCC1)(=O)=O

InChI

InChI=1S/C24H26N4O4S/c29-23(17-7-12-20-21(16-17)26-22-6-2-5-15-28(22)24(20)30)25-18-8-10-19(11-9-18)33(31,32)27-13-3-1-4-14-27/h7-12,16H,1-6,13-15H2,(H,25,29)

InChI Key

IJRIYKMOCODLMG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14855390

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.383

Distribution Coefficient, logD

2.350

Water Solubility, LogSw

-3.16

Polar Surface Area

81.191

Acid Dissociation Constant (pKa)

8.50

Base Dissociation Constant (pKb)

2.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

E475-0267 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular

References: we are preparing a list of scientific research reports with E475-0267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E475-0267?
Check Price and Availability of E475-0267, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E475-0267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E475-0267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E475-0267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E475-0267 available by request