E475-0534 Screening compound: 2-(diethylamino)ethyl 4-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}benzoate

E475-0534 Screening compound: 2-(diethylamino)ethyl 4-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}benzoate
E475-0534 Screening compound: 2-(diethylamino)ethyl 4-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E475-0534
2-(diethylamino)ethyl 4-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E475-0534

Molecular Formula

C25H27N3O5 (C25 H27 N3 O5)

Compound Name

2-(diethylamino)ethyl 4-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}benzoate

IUPAC name

2-(diethylamino)ethyl 4-{8-methyl-4H-chromeno[34-d][12]oxazole-3-amido}benzoate

SMILES

CCN(CC)CCOC(c(cc1)ccc1NC(c1noc-2c1COc1c2cc(C)cc1)=O)=O

InChI

InChI=1S/C25H27N3O5/c1-4-28(5-2)12-13-31-25(30)17-7-9-18(10-8-17)26-24(29)22-20-15-32-21-11-6-16(3)14-19(21)23(20)33-27-22/h6-11,14H,4-5,12-13,15H2,1-3H3,(H,26,29)

InChI Key

ADKOSNWHABIOQC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14855568

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.713

Distribution Coefficient, logD

3.744

Water Solubility, LogSw

-4.34

Polar Surface Area

78.319

Acid Dissociation Constant (pKa)

10.05

Base Dissociation Constant (pKb)

8.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

E475-0534 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E475-0534 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E475-0534?
Check Price and Availability of E475-0534, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E475-0534 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E475-0534
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E475-0534
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E475-0534 available by request