E475-0584 Screening compound: methyl 3-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}thiophene-2-carboxylate

E475-0584 Screening compound: methyl 3-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}thiophene-2-carboxylate
E475-0584 Screening compound: methyl 3-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}thiophene-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E475-0584
methyl 3-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}thiophene-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E475-0584

Molecular Formula

C18H14N2O5S (C18 H14 N2 O5 S)

Compound Name

methyl 3-{8-methyl-4H-chromeno[3,4-d][1,2]oxazole-3-amido}thiophene-2-carboxylate

IUPAC name

methyl 3-{8-methyl-4H-chromeno[34-d][12]oxazole-3-amido}thiophene-2-carboxylate

SMILES

Cc(cc1)cc-2c1OCc1c2onc1C(Nc1c(C(OC)=O)scc1)=O

InChI

InChI=1S/C18H14N2O5S/c1-9-3-4-13-10(7-9)15-11(8-24-13)14(20-25-15)17(21)19-12-5-6-26-16(12)18(22)23-2/h3-7H,8H2,1-2H3,(H,19,21)

InChI Key

DURKTLIHRPCRCQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14855608

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.409

Distribution Coefficient, logD

3.157

Water Solubility, LogSw

-3.78

Polar Surface Area

75.354

Acid Dissociation Constant (pKa)

7.50

Base Dissociation Constant (pKb)

-6.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

E475-0584 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E475-0584 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E475-0584?
Check Price and Availability of E475-0584, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E475-0584 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E475-0584
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E475-0584
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E475-0584 available by request