E524-0048 Screening compound: 5-{2-[4-(4-methoxyphenyl)piperazino]-2-oxoethyl}pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

E524-0048 Screening compound: 5-{2-[4-(4-methoxyphenyl)piperazino]-2-oxoethyl}pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one
E524-0048 Screening compound: 5-{2-[4-(4-methoxyphenyl)piperazino]-2-oxoethyl}pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E524-0048
5-{2-[4-(4-methoxyphenyl)piperazino]-2-oxoethyl}pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E524-0048

Molecular Formula

C23H23N5O3 (C23 H23 N5 O3)

Compound Name

5-{2-[4-(4-methoxyphenyl)piperazino]-2-oxoethyl}pyrido[2,3-e]pyrrolo[1,2-a]pyrazin-6(5H)-one

IUPAC name

8-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-2810-triazatricyclo[7.4.0.0^{26}]trideca-1(13)35911-pentaen-7-one

SMILES

COc(cc1)ccc1N(CC1)CCN1C(CN(C1=O)c2ncccc2-n2c1ccc2)=O

InChI

InChI=1S/C23H23N5O3/c1-31-18-8-6-17(7-9-18)25-12-14-26(15-13-25)21(29)16-28-22-19(4-2-10-24-22)27-11-3-5-20(27)23(28)30/h2-11H,12-16H2,1H3

InChI Key

BUFYZQRFEUAOEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14894710

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.395

Distribution Coefficient, logD

2.394

Water Solubility, LogSw

-2.47

Polar Surface Area

54.493

Acid Dissociation Constant (pKa)

19.01

Base Dissociation Constant (pKb)

7.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

E524-0048 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

Dark Chemical Matter Library (18430 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Structure:
  • Pool

References: we are preparing a list of scientific research reports with E524-0048 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E524-0048?
Check Price and Availability of E524-0048, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E524-0048 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E524-0048
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E524-0048
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E524-0048 available by request