E524-1468 Screening compound: 4-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]-N~1~-(2,3,4-trimethoxyphenethyl)butanamide

E524-1468 Screening compound: 4-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]-N~1~-(2,3,4-trimethoxyphenethyl)butanamide
E524-1468 Screening compound: 4-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]-N~1~-(2,3,4-trimethoxyphenethyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E524-1468
4-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]-N~1~-(2,3,4-trimethoxyphenethyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E524-1468

Molecular Formula

C25H28N4O5 (C25 H28 N4 O5)

Compound Name

4-[6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazin-5(6H)-yl]-N~1~-(2,3,4-trimethoxyphenethyl)butanamide

IUPAC name

4-{7-oxo-2810-triazatricyclo[7.4.0.0^{26}]trideca-1(13)35911-pentaen-8-yl}-N-[2-(234-trimethoxyphenyl)ethyl]butanamide

SMILES

COc(ccc(CCNC(CCCN(C1=O)c2ncccc2-n2c1ccc2)=O)c1OC)c1OC

InChI

InChI=1S/C25H28N4O5/c1-32-20-11-10-17(22(33-2)23(20)34-3)12-14-26-21(30)9-6-16-29-24-18(7-4-13-27-24)28-15-5-8-19(28)25(29)31/h4-5,7-8,10-11,13,15H,6,9,12,14,16H2,1-3H3,(H,26,30)

InChI Key

MKMSMOFJWYGOJX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14895069

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.136

Distribution Coefficient, logD

2.136

Water Solubility, LogSw

-2.63

Polar Surface Area

74.652

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

5.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

E524-1468 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

Dark Chemical Matter Library (18430 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Pool

References: we are preparing a list of scientific research reports with E524-1468 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E524-1468?
Check Price and Availability of E524-1468, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E524-1468 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E524-1468
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E524-1468
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E524-1468 available by request