E570-0200 Screening compound: 11-{[1-(cyclopropylcarbonyl)-2-methyl-2,3-dihydro-1H-indol-5-yl]sulfonyl}-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one

E570-0200 Screening compound: 11-{[1-(cyclopropylcarbonyl)-2-methyl-2,3-dihydro-1H-indol-5-yl]sulfonyl}-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one
E570-0200 Screening compound: 11-{[1-(cyclopropylcarbonyl)-2-methyl-2,3-dihydro-1H-indol-5-yl]sulfonyl}-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-0200
11-{[1-(cyclopropylcarbonyl)-2-methyl-2,3-dihydro-1H-indol-5-yl]sulfonyl}-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-0200

Molecular Formula

C24H27N3O4S (C24 H27 N3 O4 S)

Compound Name

11-{[1-(cyclopropylcarbonyl)-2-methyl-2,3-dihydro-1H-indol-5-yl]sulfonyl}-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one

IUPAC name

11-[(1-cyclopropanecarbonyl-2-methyl-23-dihydro-1H-indol-5-yl)sulfonyl]-711-diazatricyclo[7.3.1.0^{27}]trideca-24-dien-6-one

SMILES

CC(C1)N(C(C2CC2)=O)c(cc2)c1cc2S(N(CC(C1)CN23)CC1C3=CC=CC2=O)(=O)=O

InChI

InChI=1S/C24H27N3O4S/c1-15-9-18-11-20(7-8-22(18)27(15)24(29)17-5-6-17)32(30,31)25-12-16-10-19(14-25)21-3-2-4-23(28)26(21)13-16/h2-4,7-8,11,15-17,19H,5-6,9-10,12-14H2,1H3

InChI Key

MZFPFKDFLMWMDR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899440

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.151

Distribution Coefficient, logD

3.151

Water Solubility, LogSw

-3.48

Polar Surface Area

62.789

Acid Dissociation Constant (pKa)

21.65

Base Dissociation Constant (pKb)

-1.63

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

50.00

E570-0200 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E570-0200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-0200?
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What is the minimum amount of E570-0200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-0200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-0200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-0200 available by request