E570-4228 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-methyl-N-(pyridin-2-yl)butanamide

E570-4228 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-methyl-N-(pyridin-2-yl)butanamide
E570-4228 Screening compound: 2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-methyl-N-(pyridin-2-yl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E570-4228
2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-methyl-N-(pyridin-2-yl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E570-4228

Molecular Formula

C21H26N4O4S (C21 H26 N4 O4 S)

Compound Name

2-(1-acetyl-2-methyl-2,3-dihydro-1H-indole-5-sulfonamido)-3-methyl-N-(pyridin-2-yl)butanamide

IUPAC name

2-(1-acetyl-2-methyl-23-dihydro-1H-indole-5-sulfonamido)-3-methyl-N-(pyridin-2-yl)butanamide

SMILES

CC(C)C(C(Nc1ncccc1)=O)NS(c(cc1)cc(CC2C)c1N2C(C)=O)(=O)=O

InChI

InChI=1S/C21H26N4O4S/c1-13(2)20(21(27)23-19-7-5-6-10-22-19)24-30(28,29)17-8-9-18-16(12-17)11-14(3)25(18)15(4)26/h5-10,12-14,20,24H,11H2,1-4H3,(H,22,23,27)

InChI Key

JRULSANVDXDNNS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14899995

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.514

Distribution Coefficient, logD

2.511

Water Solubility, LogSw

-2.96

Polar Surface Area

89.897

Acid Dissociation Constant (pKa)

9.47

Base Dissociation Constant (pKb)

3.33

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

38.10

E570-4228 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Endocrine
Targets:
  • Proteases
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E570-4228 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E570-4228?
Check Price and Availability of E570-4228, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E570-4228 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E570-4228
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E570-4228
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E570-4228 available by request