E614-0168 Screening compound: 4-{6-[4-(3-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]pyridazin-3-yl}morpholine

E614-0168 Screening compound: 4-{6-[4-(3-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]pyridazin-3-yl}morpholine
E614-0168 Screening compound: 4-{6-[4-(3-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]pyridazin-3-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound E614-0168
4-{6-[4-(3-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]pyridazin-3-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E614-0168

Molecular Formula

C17H23N7O2 (C17 H23 N7 O2)

Compound Name

4-{6-[4-(3-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]pyridazin-3-yl}morpholine

IUPAC name

4-{6-[4-(3-methyl-1H-pyrazole-5-carbonyl)piperazin-1-yl]pyridazin-3-yl}morpholine

SMILES

Cc1n[nH]c(C(N(CC2)CCN2c(cc2)nnc2N2CCOCC2)=O)c1

InChI

InChI=1S/C17H23N7O2/c1-13-12-14(19-18-13)17(25)24-6-4-22(5-7-24)15-2-3-16(21-20-15)23-8-10-26-11-9-23/h2-3,12H,4-11H2,1H3,(H,18,19)

InChI Key

SHVCLYPAUSKJJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14904374

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.983

Distribution Coefficient, logD

0.979

Water Solubility, LogSw

-1.98

Polar Surface Area

74.746

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

7.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.90

E614-0168 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E614-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E614-0168?
Check Price and Availability of E614-0168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E614-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E614-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E614-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E614-0168 available by request