E626-1176 Screening compound: N-[(4-ethylphenyl)methyl]-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-3-carboxamide

E626-1176 Screening compound: N-[(4-ethylphenyl)methyl]-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-3-carboxamide
E626-1176 Screening compound: N-[(4-ethylphenyl)methyl]-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E626-1176
N-[(4-ethylphenyl)methyl]-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E626-1176

Molecular Formula

C25H26FN5OS (C25 H26 FN5 OS)

Compound Name

N-[(4-ethylphenyl)methyl]-1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperidine-3-carboxamide

IUPAC name

N-[(4-ethylphenyl)methyl]-1-[6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]piperidine-3-carboxamide

SMILES

CCc1ccc(CNC(C(CCC2)CN2c(s2)nn3c2nc(-c(cc2)ccc2F)c3)=O)cc1

InChI

InChI=1S/C25H26FN5OS/c1-2-17-5-7-18(8-6-17)14-27-23(32)20-4-3-13-30(15-20)25-29-31-16-22(28-24(31)33-25)19-9-11-21(26)12-10-19/h5-12,16,20H,2-4,13-15H2,1H3,(H,27,32)/t20-/m0/s1

InChI Key

RHCSYDWLFNAWNN-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD14905150

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.939

Distribution Coefficient, logD

4.939

Water Solubility, LogSw

-4.44

Polar Surface Area

48.873

Acid Dissociation Constant (pKa)

12.49

Base Dissociation Constant (pKb)

3.32

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

32.00

E626-1176 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E626-1176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E626-1176?
Check Price and Availability of E626-1176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E626-1176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E626-1176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E626-1176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E626-1176 available by request