E629-0132 Screening compound: N-[2-(4-sulfamoylphenyl)ethyl]-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

E629-0132 Screening compound: N-[2-(4-sulfamoylphenyl)ethyl]-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide
E629-0132 Screening compound: N-[2-(4-sulfamoylphenyl)ethyl]-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E629-0132
N-[2-(4-sulfamoylphenyl)ethyl]-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E629-0132

Molecular Formula

C22H21N3O3S2 (C22 H21 N3 O3 S2)

Compound Name

N-[2-(4-sulfamoylphenyl)ethyl]-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

IUPAC name

N-[2-(4-sulfamoylphenyl)ethyl]-2-[2-(thiophen-2-yl)-1H-indol-1-yl]acetamide

SMILES

NS(c1ccc(CCNC(Cn(c(-c2cccs2)c2)c3c2cccc3)=O)cc1)(=O)=O

InChI

InChI=1S/C22H21N3O3S2/c23-30(27,28)18-9-7-16(8-10-18)11-12-24-22(26)15-25-19-5-2-1-4-17(19)14-20(25)21-6-3-13-29-21/h1-10,13-14H,11-12,15H2,(H,24,26)(H2,23,27,28)

InChI Key

GYJHYRDSOHXFDI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27600625

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.969

Distribution Coefficient, logD

2.968

Water Solubility, LogSw

-3.56

Polar Surface Area

76.355

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

0.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

E629-0132 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E629-0132 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E629-0132?
Check Price and Availability of E629-0132, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E629-0132 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E629-0132
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E629-0132
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E629-0132 available by request