E629-0288 Screening compound: 1-(4-propylpiperazin-1-yl)-2-[2-(thiophen-2-yl)-1H-indol-1-yl]ethan-1-one

E629-0288 Screening compound: 1-(4-propylpiperazin-1-yl)-2-[2-(thiophen-2-yl)-1H-indol-1-yl]ethan-1-one
E629-0288 Screening compound: 1-(4-propylpiperazin-1-yl)-2-[2-(thiophen-2-yl)-1H-indol-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E629-0288
1-(4-propylpiperazin-1-yl)-2-[2-(thiophen-2-yl)-1H-indol-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E629-0288

Molecular Formula

C21H25N3OS (C21 H25 N3 OS)

Compound Name

1-(4-propylpiperazin-1-yl)-2-[2-(thiophen-2-yl)-1H-indol-1-yl]ethan-1-one

IUPAC name

1-(4-propylpiperazin-1-yl)-2-[2-(thiophen-2-yl)-1H-indol-1-yl]ethan-1-one

SMILES

CCCN(CC1)CCN1C(Cn(c(-c1cccs1)c1)c2c1cccc2)=O

InChI

InChI=1S/C21H25N3OS/c1-2-9-22-10-12-23(13-11-22)21(25)16-24-18-7-4-3-6-17(18)15-19(24)20-8-5-14-26-20/h3-8,14-15H,2,9-13,16H2,1H3

InChI Key

MFVYNMKHYRAZMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27600669

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.52

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.836

Distribution Coefficient, logD

3.653

Water Solubility, LogSw

-3.88

Polar Surface Area

21.622

Acid Dissociation Constant (pKa)

22.56

Base Dissociation Constant (pKb)

7.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

E629-0288 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with E629-0288 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E629-0288?
Check Price and Availability of E629-0288, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E629-0288 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E629-0288
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E629-0288
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E629-0288 available by request