E643-0097 Screening compound: 2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxyphenyl)butanamide

E643-0097 Screening compound: 2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxyphenyl)butanamide
E643-0097 Screening compound: 2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxyphenyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E643-0097
2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxyphenyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E643-0097

Molecular Formula

C17H18N4O2S (C17 H18 N4 O2 S)

Compound Name

2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxyphenyl)butanamide

IUPAC name

2-{3H-imidazo[45-b]pyridin-2-ylsulfanyl}-N-(2-methoxyphenyl)butanamide

SMILES

CCC(C(Nc(cccc1)c1OC)=O)Sc([nH]1)nc2c1nccc2

InChI

InChI=1S/C17H18N4O2S/c1-3-14(16(22)19-11-7-4-5-9-13(11)23-2)24-17-20-12-8-6-10-18-15(12)21-17/h4-10,14H,3H2,1-2H3,(H,19,22)(H,18,20,21)/t14-/m0/s1

InChI Key

MXSUHRZWIIHOAT-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD14906917

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

342.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.046

Distribution Coefficient, logD

3.040

Water Solubility, LogSw

-3.38

Polar Surface Area

58.649

Acid Dissociation Constant (pKa)

11.98

Base Dissociation Constant (pKb)

3.72

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.50

E643-0097 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Purinergic Library (3321 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Proteases
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with E643-0097 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E643-0097?
Check Price and Availability of E643-0097, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E643-0097 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E643-0097
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E643-0097
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E643-0097 available by request