E667-0218 Screening compound: N-(5-CHLOROPYRIDIN-2-YL)-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-6-SULFONAMIDE

E667-0218 Screening compound: N-(5-CHLOROPYRIDIN-2-YL)-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-6-SULFONAMIDE
E667-0218 Screening compound: N-(5-CHLOROPYRIDIN-2-YL)-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-6-SULFONAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound E667-0218
N-(5-CHLOROPYRIDIN-2-YL)-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-6-SULFONAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E667-0218

Molecular Formula

C17H16ClN3O2S (C17 H16 ClN3 O2 S)

Compound Name

N-(5-CHLOROPYRIDIN-2-YL)-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-6-SULFONAMIDE

IUPAC name

n/a

SMILES

O=S(c(cc1)cc2c1[nH]c1c2CCCC1)(Nc(cc1)ncc1Cl)=O

InChI

InChI=1S/C17H16ClN3O2S/c18-11-5-8-17(19-10-11)21-24(22,23)12-6-7-16-14(9-12)13-3-1-2-4-15(13)20-16/h5-10,20H,1-4H2,(H,19,21)

InChI Key

LJLHAYJXGKNUIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14908884

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.85

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.600

Distribution Coefficient, logD

1.053

Water Solubility, LogSw

-3.84

Polar Surface Area

61.363

Acid Dissociation Constant (pKa)

4.86

Base Dissociation Constant (pKb)

-1.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

E667-0218 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Others
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E667-0218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E667-0218?
Check Price and Availability of E667-0218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E667-0218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E667-0218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E667-0218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E667-0218 available by request