E677-1051 Screening compound: N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)furan-2-carboxamide

E677-1051 Screening compound: N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)furan-2-carboxamide
E677-1051 Screening compound: N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E677-1051
N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E677-1051

Molecular Formula

C18H21N3O3S (C18 H21 N3 O3 S)

Compound Name

N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)furan-2-carboxamide

IUPAC name

N-[3-(dimethylamino)propyl]-N-(4-methoxy-13-benzothiazol-2-yl)furan-2-carboxamide

SMILES

CN(C)CCCN(C(c1ccco1)=O)c1nc(c(OC)ccc2)c2s1

InChI

InChI=1S/C18H21N3O3S/c1-20(2)10-6-11-21(17(22)14-8-5-12-24-14)18-19-16-13(23-3)7-4-9-15(16)25-18/h4-5,7-9,12H,6,10-11H2,1-3H3

InChI Key

MERYCIXZCINBBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11985727

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

359.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.027

Distribution Coefficient, logD

0.879

Water Solubility, LogSw

-3.14

Polar Surface Area

46.220

Acid Dissociation Constant (pKa)

25.30

Base Dissociation Constant (pKb)

9.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E677-1051 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

CNS BBB Library (22607 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E677-1051 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E677-1051?
Check Price and Availability of E677-1051, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E677-1051 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E677-1051
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E677-1051
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E677-1051 available by request