E677-1143 Screening compound: 3-(benzenesulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide

E677-1143 Screening compound: 3-(benzenesulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide
E677-1143 Screening compound: 3-(benzenesulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E677-1143
3-(benzenesulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E677-1143

Molecular Formula

C22H27N3O4S2 (C22 H27 N3 O4 S2)

Compound Name

3-(benzenesulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide

IUPAC name

3-(benzenesulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-13-benzothiazol-2-yl)propanamide

SMILES

CN(C)CCCN(C(CCS(c1ccccc1)(=O)=O)=O)c1nc(c(OC)ccc2)c2s1

InChI

InChI=1S/C22H27N3O4S2/c1-24(2)14-8-15-25(22-23-21-18(29-3)11-7-12-19(21)30-22)20(26)13-16-31(27,28)17-9-5-4-6-10-17/h4-7,9-12H,8,13-16H2,1-3H3

InChI Key

NTLRBRADFHKEGP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11985747

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

461.61

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.053

Distribution Coefficient, logD

0.847

Water Solubility, LogSw

-3.50

Polar Surface Area

66.150

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

9.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

E677-1143 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

CNS targets activity set (6557 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with E677-1143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E677-1143?
Check Price and Availability of E677-1143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E677-1143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E677-1143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E677-1143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E677-1143 available by request